1
For instance, alternatively spliced truncated p53 isoform termed p47 inhibits wild-type p53-induced apoptosis through suppression of wild-type p53-mediated transcriptional action [39]. Truncated Survivin-2a isoform attenuates the anti-apoptotic activity of wild-type Survivin, possibly via immediate interaction with wild-type Survivin [40]. These examples, alongside one another with our existing ou