Ld be valuable for much better comprehension of the system of WTLd be useful for greater idea of the mechanism of WT1-mediated leukemogenesis and tumorigenesis. On this research, Ex4a(+)WT1 isoform inhibited the transcriptional activation of Bcl-xL and Bcl-2 genes by important WT1 isoform [17AA(+)KTS(-)WT1]. It had been claimed that major WT1 isoform exerts transcriptional action through the